Enantioselective Synthesis Of Beta-Amino Acids
ISBN : 9780471467380
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Enantioselective Synthesis of Beta-Amino Acids
Covers all facets of the synthesis of ß-amino acidsAs evidenced by an exponential increase in the literature publishedon the subject, interest in ß-amino acids has grown over thepast several years. With major pharmaceutical applications, theseamino acids are now studied across multiple lines of research,including combinatorial chemistry, medicinal chemistry, moleculardesign, proteomics, and others.This Second Edition of Enantioselective Synthesis of ß-AminoAcids updates reviews included in the First Edition while alsocovering new developments since its publication. The book presentsdetailed discussions of the most important methods for thesynthesis of ß-amino acids. In most cases, the lead chemistwho originally developed a method provides an authoritativedescription of it.In addition, Enantioselective Synthesis of ß-Amino Acids,Second Edition:* Features introductory overviews on the structural types ofrelevant ß-amino acid targets and salient ß-amino acidspresent in natural products* Dedicates several chapters to advances in the synthesis ofoligomers from ß-amino acids* Includes general and practical procedures for the preparation ofß-amino acids in each chapter* Discusses the most important methods that have been recentlydeveloped for the asymmetric synthesis of cyclic and open-chainß-amino acids* Includes a report on the preparation of libraries of enantiopureß-amino acids using combinatorial approachesThe only book of its kind available today, EnantioselectiveSynthesis of ß-Amino Acids, Second Edition offers upper-levelstudents and professionals an essential resource for pharmaceuticaldevelopment, medicinal chemistry, and biochemistry.
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