Insulin Resistance: A Clinical Handbook (Paperback)

Insulin Resistance: A Clinical Handbook

The objective of this book is to summarize the current state ofknowledge about insulin resistance. Section 1 (Pathophysiology ofInsulin Resistance) considers the development of current conceptsof insulin resistance. This is followed by a critical review oftechniques for the assessment of insulin action in humans. Thesection concludes with an outline of current hypotheses concerningthe molecular defects responsible for insulin resistance. Section 2(Insulin Resistance in Clinical Medicine) broadens the discussionto include physiological and pathological conditions with whichinsulin resistance is associated; the effects of drug treatment oninsulin sensitivity are also considered. Section 3 (Management ofInsulin Resistance and Associated Conditions) focuses on theavoidance and treatment of insulin resistance in its clinicalmanifestations. A discussion of the potential benefits ofnon-pharmacological measures prefaces a review of the range ofdrugs used in the treatment of type 2 diabetes and relateddisorders. References are confined to key articles at the end ofeach section.