Title
A Novel Pulsatile Drug Delivery System With Colon Specificity: A Complete Overview of Pulsatile Drug Delivery System,Used
Delivery time: 8-12 business days (International)
The aim of current study was to investigate the invitro performance of compress coated tablet of Atenolol. Administration of conventional tablet has been reported to exhibit fluctuation in the plasma drug level, resulting either in manifestation of side effect or reduction in drug concentration at the receptor site. Atenolol has strong absorption throughout GIT as well as in colon. But, it causes GI irritation problem. Hence it is always effective to have absorption of Atenolol at Colon site. A novel colon targeted tablet formulation was developed by press coating rapidly disintegrating tablet of Atenolol with HPMC K100M, guar gum and Eudragit S100 as barrier layer. The device was enteric coated so that variability in gastric emptying time can be overcome and a colon specific release can be achieved. Different combinations of polymers were selected to achieve suitable lag time for the treatment of hypertension. Invitro release study was carried out for prepared tablets, showed that the tablet coated with HPMC K100M, guar gum and Eudragit S100 have limited drug release in stomach and small intestinal environment and released maximum amount of drug in the colonic environment.
By changing our most important processes and
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.