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ActinBinding Proteins and Disease (Protein Reviews, 8),Used
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Actin is a ubiquitous protein present in high concentrations in virtually all cells. It's assembly and disassembly is modulated by more than 100 actinbinding proteins. These interactions are essential for a variety of important cellular processes including cell division, gene expression and motility.There are scattered reports in the published literature citing relationships between actin, actinbinding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders.This volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole. Additionally, clinicians will be interested because the book explains the role of cytoskeletal proteins in various diseases, including cancer and immune system disorders.
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