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ADPRibosylation: Metabolic Effects and Regulatory Functions (Developments in Molecular and Cellular Biochemistry, 12),Used
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Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADPribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other posttranslational modifications such as phosphorylation, has not been generally recognized. While it is not feasible to cover all aspects of ADPribosylation, the thirtyone articles contained in this volume provide a valuable overview of recent progress in the field within the context of cell control mechanisms. For the convenience of the reader, the various topics have been grouped into several sections: (a) poly(ADPribosyl)ation; (b) monoADPribosylation; (c) toxin monoADPribosylation; (d) inhibitors and activators; (e) protein modification with ADPribose and its analogues; and (f) nonmodification forms of ADPribose. The contents of the individual chapters reflect the ideas of the contributors, many of whom have spent their careers attempting to resolve the biological functions of ADPribosylation. We hope that this publication will serve as a useful reference for those investigators that are new to the area as well as those who are actively studying ADPribosylation.
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