Title
Amino Acid Conjugates Of Aceclofenac: A prodrug approach to modify NSAID,Used
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Majority of the agents which are nonselective COX1 and COX2 inhibitors, shares the undesirable effect to gastric and intestinal mucosa, resulting in erosion, ulcers and represent the major adverse reactions to the use of NSAIDs. The belief behind this book is to bring in one new method for upgrading solubility behavior by amino acid conjugation and thereby overcome general side effects of NSAID. Prodrug is a chemically modified inert drug precursor, which upon biotransformation lead to activation and produce pharmacological action. In this book prodrug approach stands for modification to overcome pharmaceutical barriers like solubility behavior. Even if the amino acid conjugates formerly classified under prodrug but it defeat the limitation of them such as formation of unforeseen metabolite and disagreeable side effects. Some conjugate has maximum water solubility than parent compound. The partition coefficient of the synthesized compound was found to be more than the parent drug. It indicates that conjugates synthesized with hydrophilic amino acid possess more water solubility. In future this approach can be applied to other NSAIDs having free carboxyl functional group.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
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