Title
Analysis of viriato gene function during Drosophila Development: Molecular and Cellular Analysis of the Function of viriato Gene,Used
Delivery time: 8-12 business days (International)
A precise coordination between cell growth, proliferation, differentiation and apoptosis is required in the development of multicellular organisms. In an ongoing screen to identify novel genes required for proper growth and patterning of the Drosophila eye, we have identified viriato (vito), the sole fruitfly homologue of the vertebrate Nol12 proteins. In this thesis we report the characterization of vito function during Drosophila development. We report that vito/Nol12 plays a crucial role in tissue growth independently of its role in cell survival. We showed that the Vito protein localizes to the nucleolus, regulating the structure and main molecular events of this subnuclear compartment in a dynamic manner. We have further shown that dMyc controls vito levels to regulate nucleolar architecture and that vito is required for dMyc to reach its full potential as a potent cell growth inducer. We further describe a targeted double RNAi screen performed in order to get a deep knowledge about the pathways working with vito during eye development. Further investigation culminated with the identification of a strong genetic interaction between vito and TGF signaling pathway.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.