Title
Antigenpresentation of nonpeptidic antigens: Trafficking, loading and presentation of lipids and small metabolites,Used
Delivery time: 8-12 business days (International)
T cells recognize a broad variety of antigens, including peptides, lipids and nonpeptidic phosphorylated metabolites. Clarification of the rules rendering nonpeptidic molecules immunogenic is essential to understand and to influence the reactions of the immune system to this class of substances in health and disease. Molecular mechanisms governing the immunogenicity of nonpeptidic ligands such as their cell internalization, trafficking within intracellular organelles, association with dedicated antigenpresenting molecules, induction of central and peripheral tolerance, and finally their role in autoimmune diseases as well as in protection during infection are unknown to date. The aims were to assess the cell biological rules of immunogenicity and immunological functions of nonpeptidic antigens, with particular emphasis on cell trafficking of nonpeptidic antigens and antigenpresenting molecules focusing on the reactivity and presence of invariant natural killer T cells in disease, the role of CD1a trafficking in lipid antigen presentation, and the requirements for membrane translocation of phosphorylated mevalonate metabolites that stimulate T cell receptor gammadelta cells.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.