Title
Arachidonic Acid Metabolism and Tumor Promotion (Prostaglandins, Leukotrienes, and Cancer, 3),Used
Delivery time: 8-12 business days (International)
Prostaglandins, Leukotrienes, and Cancer is a multivolume series that will focus on an emerging area of cancer research. In 1968, R.H. Williams first reported that elevated prostaglandin levels are present in human medullary car cinoma. Since that time, the concept that arachidonic acid metabolites may be in volved in cancer has expanded to include every aspect of the disease from cell transformation through metastasis. Prostaglandins and leukotrienes are generic terms used to describe a family of bioactive lipids produced from unsaturated fatty acids (principally from and lipoxygenase pathways, respec arachidonic acid) via the cyclooxygenase tively. Cyclooxygenase products consist of diverse products such as prosta glandin E2 (POE), prostacyclin (POI) and thromboxane A2 (TXA), whereas 2 2 2 lipoxygenase products consist of hydroperoxy fatty acids and mono, di and trihydroxy acids including leukotrienes. The precursor fatty acids for the cyclooxygenase and lipoxygenase pathways are present in cellular phospholipids. This finding established an important control point in their biosynthesisthe release of substrate. This occurs in response to numerous stimuli that act at the cell surface. Dr. Bengt Samuelsson's extensive study of the metabolism of pros taglandins indicated that they are rapidly inactivated on a single pass through pulmonary circulation. Thus, they cannot act as circulating hormones and appear to be made on demand in or in the vicinity of target tissues leading to the concept that prostaglandins are local hormones or autocoids.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Frequently Asked Questions
- Q: What is the main topic of the book 'Arachidonic Acid Metabolism and Tumor Promotion'? A: The book focuses on the role of arachidonic acid metabolites in cancer research, particularly their involvement in various aspects of the disease from cell transformation to metastasis.
- Q: Who is the author of 'Arachidonic Acid Metabolism and Tumor Promotion'? A: The author of the book is Susan M. Fischer.
- Q: What type of binding does this book have? A: This book is bound in hardcover.
- Q: When was 'Arachidonic Acid Metabolism and Tumor Promotion' published? A: The book was published on April 30, 1985.
- Q: How many pages are in the book? A: The book contains 272 pages.
- Q: What condition is the book in? A: The book is listed as 'New'.
- Q: What is the significance of arachidonic acid in cancer research? A: Arachidonic acid is significant in cancer research as its metabolites, such as prostaglandins and leukotrienes, are believed to play a role in cancer development and progression.
- Q: Is 'Arachidonic Acid Metabolism and Tumor Promotion' part of a series? A: Yes, it is part of the multi-volume series titled 'Prostaglandins, Leukotrienes, and Cancer'.
- Q: What are some of the bioactive lipids discussed in the book? A: The book discusses various bioactive lipids including prostaglandin E2, prostacyclin, and thromboxane A2, which are produced from arachidonic acid.
- Q: What is the primary audience for this book? A: The primary audience includes researchers and professionals in the fields of cancer research, biochemistry, and molecular biology.