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If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
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All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
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El empaquetamiento del DNA y su accesibilidad en el ncleo celular eucariota estn supeditados a la interaccin de esta molcula con diferentes tipos de protenas cromosmicas, siendo las histonas las de mayor relevancia. La importancia de histonas y cromatina en el metabolismo nuclear ha motivado una gran cantidad de estudios en sistemas modelo, principalmente mamferos, donde la complejidad del metabolismo cromatnico refleja la gran heterogeneidad estructural y funcional de las histonas. Sin embargo, el conocimiento de la dinmica cromatnica en animales protstomos es todava muy escaso. Dada la relevancia de este linaje de animales para comprender la evolucin de metazoos, adems de la presencia de organismos con importancia comercial en dicho grupo, el presente trabajo ha llevado a cabo la caracterizacin molecular y evolutiva de histonas en un molusco bivalvo de la familia de los pectnidos. Nuestros resultados revelan la presencia de secuencias de histonas conservadas y sometidas a constricciones selectivas tanto a nivel proteico como nucleotdico, probablemente dirigidas a mantener unas propiedades electrostticas adecuadas para la correcta configuracin de la cromatina.
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