Title
Biochemistry and Genetics of RecqHelicases,Used
Delivery time: 8-12 business days (International)
Biochemistry And Genetics of RecQHelicases provides a background into the role of helicases in general and RecQ helicases specifically in DNA repair. Helicases enzymes which break down hydrogen bonds between nucleic acid strands in a nucleoside triphosphatedependent mannerare ubiquitous in biology, participating in processes as diverse as replication, repair, recombination, transcription, and translation. The RecQfamily helicases are a group of helicases which have important roles in the maintenance of genomic stability in many organisms. In humans, mutations in three RecQfamily helicases lead to disease. This book thoroughly examines these helicases. Mutations in the BLM gene lead to Bloom syndrome, a disorder characterized by a susceptibility to many types of cancer. Mutations in the WRN gene cause Werner syndrome, a disease which in some respects resembles premature aging. Finally, mutations in a newly characterized RecQfamily member, RECQ4, may lead to the very rare recessive disorder RothmundThomson syndrome, a condition characterized by developmental abnormalities and some aginglike manifestations. This book is intended for any researchers invested in these particular disorders, or with a general interest in DNA.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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