Brain Development: Roles of Transient Neurons in Corpus Callosum Formation and Guidance,Used

Brain Development: Roles of Transient Neurons in Corpus Callosum Formation and Guidance,Used

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The brain is a main center for control over the other organs in all vertebrate. It is responsible for higherorder functions like processing environmental stimuli or language and it is divided in two hemispheres. In order to achieve such tasks, the right and left sides need to be connected and the corpus callosum is the major bridge (over 200 mio. of axons) channeling and coordinating information between these two hemispheres. Previous works have shown that glial cells (nonneuronal brain cells) found at the midline of the brain are essential for guiding the projections from one side to the other side. We found that two populations of neuronal cells are also required for the proper formation of the corpus callosum and for the guidance of interhemispheric axons during embryonic development. Similar mechanisms could occur in humans and observations of human pathologies with defects in corpus callosum formation suggest that these neurons could be involved. This work thus gives new insights into how neurons together with their glial partners have the ability to shape the corpus callosum, a potential process for guidance in other brain regions.

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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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