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Help
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
Cartilage is a connective tissue integral to the functioning of joints. A promising step in treating defective cartilage is the implantation of autologous bone marrow stem cells at the defect site. When carried by an appropriate scaffold to provide chondrogenic signals, bone marrow stem cells can differentiate into cartilage. Previous studies show that cells seeded in hydrogels without the inclusion of fibers experience cellmediated contraction that leads swiftly to cell mediated death; the fibers are also considered key to improving mechanical strength of hydrogels. However, after three weeks in vitro in a collagen gel 3D matrix, cells seeded in gels without fibers did not have significantly different cell viability percentages than cells seeded in gels with flat fibers or round fibers. Additionally, compressive testing at 10% strain indicated that the equilibrium stresses of gels with no fibers was significantly higher than equilibrium stresses of gels containing flat fibers. Therefore, the inclusion of fibers and the use of compressive stimulation conditioning may not be any more effective than simple tissue engineered constructs of cellseeded collagen gels.
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This product may contain chemicals known to the State of California to cause cancer,
birth defects, or other reproductive harm.
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⚠️ California Proposition 65 Warning: Some products sold on this website may expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
