Title
Cancer of Uterine Cervix and PTEN tumor suppressor gene: Genetic and Epigenetic alterations in PTEN gene among Cervical Cancer p,Used
Delivery time: 8-12 business days (International)
Cancer of uterine cervix is one of the most common malignant diseases affecting women worldwide. It is responsible for almost 20 percent of all female deaths in India with almost 130,000 new cases every year. Multiple alterations are necessary for the development of this cancer in addition to the HPV infection. Comparatively a younger tumor suppressor gene, PTEN, was found to be located on chromosome 10q23.3 with nine exons and is deleted and mutated in a variety of human cancers. PTEN is expressed in normal cervical epithelium, implying that loss of function may have some consequences in cervical cancer. We analyzed carcinoma cases for detection of PTEN promoter methylation, mutation, gene expression and apoptosis. Promoter methylation was detected in 61% cases and found to be correlated with the loss of PTEN expression, suggesting that silencing of PTEN gene definitely contribute in the tumorigenesis of cervical cancer. This work is expected to attract the attention of both the clinicians and researchers in the fields of oncology.
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Shipping & Returns
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.