Chlamydia pneumoniae Lung Infection in Two Inbred Mouse Strains: Multivariate analysis of Chlamydia pneumoniae lung infection in,Used

Chlamydia pneumoniae Lung Infection in Two Inbred Mouse Strains: Multivariate analysis of Chlamydia pneumoniae lung infection in,Used

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Infections with Chlamydia pneumoniae have been associated with chronic inflammatory diseases, but the influences of multiple factors are not well understood. A multivariate experimental design investigated the major factors that influence disease, chlamydial lung burden, and transcript levels: i) host genetics, ii) prechallenge immunity, iii) time after challenge infection, iv) dietary protein content, v) dietary antioxidant content. The combined effects of mouse strain, immune status, and time after challenge inoculation resulted in opposite outcomes for lung disease and elimination of C. pneumoniae, while dietary protein and antioxidant content had little overall influence. A simple bestfit partial least square regression model using day3 Tim3, GATA3, and arginase 2 transcript concentrations predicted 85% of the day10 disease and 72% of the day10 C. pneumoniae lung load. This book has elucidated general mechanisms of chlamydial pathogenesis, and clearly supports the concept that hostdependent levels of early Th1 and Th2 responses, and their balance, significantly correlated with late disease and pathogen load of C. pneumoniae lung infections.

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We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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