Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series In Probability And Statistics)

Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series In Probability And Statistics)

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Learn Rigorous Statistical Methods To Ensure Valid Clinical Trialsthis Second Edition Of The Critically Hailed Clinical Trials Builds On The Text'S Reputation As A Straightforward And Authoritative Presentation Of Statistical Methods For Clinical Trials. Readers Are Introduced To The Fundamentals Of Design For Various Types Of Clinical Trials And Then Skillfully Guided Through The Complete Process Of Planning The Experiment, Assembling A Study Cohort, Assessing Data, And Reporting Results. Throughout The Process, The Author Alerts Readers To Problems That May Arise During The Course Of The Trial And Provides Commonsense Solutions.The Author Bases The Revisions And Updates On His Own Classroom Experience, As Well As Feedback From Students, Instructors, And Medical And Statistical Professionals Involved In Clinical Trials. The Second Edition Greatly Expands Its Coverage, Ranging From Statistical Principles To Controversial Topics, Including Alternative Medicine And Ethics. At The Same Time, It Offers More Pragmatic Advice For Issues Such As Selecting Outcomes, Sample Size, Analysis, Reporting, And Handling Allegations Of Misconduct. Readers Familiar With The First Edition Will Discover Completely New Chapters, Including:* Contexts For Clinical Trials* Statistical Perspectives* Translational Clinical Trials* Dosefinding And Doseranging Designseach Chapter Is Accompanied By A Summary To Reinforce The Key Points. Revised Discussion Questions Stimulate Critical Thinking And Help Readers Understand How They Can Apply Their Newfound Knowledge, And Updated References Are Provided To Direct Readers To The Most Recent Literature.This Text Distinguishes Itself With Its Accessible And Broad Coverage Of Statistical Design Methodsthe Crucial Building Blocks Of Clinical Trials And Medical Research. Readers Learn To Conduct Clinical Trials That Produce Valid Qualitative Results Backed By Rigorous Statistical Methods.

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Frequently Asked Questions

  • Q: What is the main focus of 'Clinical Trials: A Methodologic Perspective Second Edition'? A: The book focuses on rigorous statistical methods essential for designing valid clinical trials, covering comprehensive planning, data assessment, and result reporting.
  • Q: Who is the author of this book? A: The author of the book is Steven Piantadosi, who brings extensive experience in clinical trials and statistical methodologies.
  • Q: What new topics are introduced in the second edition? A: The second edition introduces new chapters on contexts for clinical trials, statistical perspectives, translational clinical trials, and dose-finding designs.
  • Q: How does this book help in understanding clinical trial design? A: The book provides clear guidance through each phase of clinical trial design and execution, along with practical advice and common pitfalls to avoid.
  • Q: Is this book suitable for beginners in clinical research? A: Yes, it is designed to be accessible for readers at various levels, making it suitable for beginners as well as experienced professionals.
  • Q: What kind of updates does the second edition include? A: The second edition includes expanded coverage of statistical principles, updates based on reader feedback, and new references to the latest literature.
  • Q: Does the book address ethical considerations in clinical trials? A: Yes, it discusses ethical issues related to clinical trials, providing insights on how to handle them appropriately.
  • Q: How many pages does the book have? A: The book contains a total of 687 pages.
  • Q: What is the binding type of this book? A: The book is available in hardcover binding, ensuring durability for repeated use.
  • Q: When was the second edition published? A: The second edition was published on January 1, 2005.