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Bringing together contributions from researchers in biogerontology, geriatric medicine, free radical chemistry and biology, oncology, cardiology, neurobiology, dermatology, pharmacology, nutrition, molecular medicine, and other fields, Cutler (Kronos Longevity Research Institute) and Rodriguez (National Institute of Standards and Technology) present a review of current understanding of oxidative stress and aging. The 47 chapters of the first volume are organized into sections discussing historical perspectives; free radical chemistry and biology; redox regulation and cell signaling; technology, biomarkers, and applications in the measurement of oxidative stress; dietary antioxidants; and endogenous antioxidants and repair. The second volume contains a further 37 chapters examining epidemiology and intervention studies, oxidative stress related diseases, aging and oxidative stress, evolutionary comparative biology of aging an longevity, longevity determinant genes an oxidative stress, noninvasive assessment of oxidative stress and therapeutic intervention, future trends in health care, and human life extension. Annotation 2006 Book News, Inc., Portland, OR (booknews.com)
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