Crystal Engineering of Active Pharmaceutical Ingredients: Multiple Component Crystal Forms and Physicochemical Property Enhancem,Used

Crystal Engineering of Active Pharmaceutical Ingredients: Multiple Component Crystal Forms and Physicochemical Property Enhancem,Used

In Stock
SKU: DADAX3659190365
Brand: LAP Lambert Academic Publishing
$113.77 $162.53
Save $48.76
Quantity
Add to wishlist
Add to compare

Processing time: 1-3 days

US Orders Ships in: 3-5 days

International Orders Ships in: 8-12 days

Return Policy: 15-days return on defective items

Payment Option
Payment Methods

Help

If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.

Customer service

All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com

Sale & Press

If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com

Enhancing the physicochemical properties of solidstate materials through crystal engineering enables optimization of these materials without covalent modification. Cocrystals have become a reliable means to generate novel crystalline forms with multiple components and they exhibit different physicochemical properties compared to the individual components. This dissertation exemplifies methodologies to generate cocrystals of active pharmaceutical ingredients (APIs) based upon knowledge of supramolecular interactions (supramolecular synthons), while focusing on enhanced delivery through in vitro and in vivo processes with both salts and cocrystals respectively. Different multiple component crystalline entities were discovered through traditional solution based techniques and with mechanochemistry involving small amounts of an appropriate solvent, or solvent drop grinding (SDG). Dissolution studies and pharmacokinetic enhancement through optimized oral drug delivery via supramolecular complexes are presented with particular attention to noncovalent intermolecular interactions.

⚠️ WARNING (California Proposition 65):

This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.

For more information, please visit www.P65Warnings.ca.gov.

Recently Viewed