Determination of Acetylated Residues in Mammalian Proteins in Silico: Analysis of Acetylated residues in Mammalian proteins by u,Used

Determination of Acetylated Residues in Mammalian Proteins in Silico: Analysis of Acetylated residues in Mammalian proteins by u,Used

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Bioinformatics is a helpful tool for experimental studies. It is less time consuming and may provide a plat form for experimental work. Post translational modification is investigated in silico, with the help of the bioinformatics tool MAPRes. This tool mines association pattern around a modified residue and nonmodified residue. In this work association rules were mined around acetylated Lys residues in proteins. For this purpose 393 proteins were collected from the dbPTM database. The rules showed by MAPRes are highest preference for Alanine, Histidine, Lysine and Glycine in modified proteins and Leucine, Alanine, Serine, Glutamic acid and Glycine in nonmodified proteins. The comparison of MAPRes analysis results for predicted Lys and nonpredicted Lys substrate sites with those of Pail, Ensemblepail and PredMod prediction methods show a high conformity level, ranging from 47% to 70%. This high rate of conformity points to the accuracy of the algorithm and the technique of data mining applied in MAPRes. This work will be helpful for determining acetyltransferases sequence specificity in proteins which will be helpful in diseases such as cancer, diabetes.

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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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