Title
Development and Production of Humanized Monoclonal Antibody: Development, Expression and Characterization of Humanized AntiC2 M,Used
Delivery time: 8-12 business days (International)
The treatment of cancer remains a formidable challenge owing to the difficulties in differentiating tumor from nontumor cells in order to ameliorate the disease without causing intolerable toxicity to human patients. The use of monoclonal antibodies (mAbs) represents an attractive approach of overcoming this problem as the mAbs can be designed to selectively target tumor cells and elicit a variety of responses once bound. However, when rodent mAbs are administered in humans, antiantibody responses are frequently observed. Hence, humanized monoclonal antibodies are instead widely used for diagnosis and treatment of cancer due to their reduced immunogenicity and high specificity. In this book, two humanization methods were utilized for the development of humanized mAb (humC2 mAbs) against C2antigen, a marker expressed in colorectal and ovarian cancer, from mAb of mouse origin. Various procedures were also developed to produce humC2 mAbs, with high efficiency in terms continuity of production, lowered cost and increased speed. In addition, highthroughput and automated systems were also utilized to facilitate the upstream and downstream phases of humC2 mAbs.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.