Development and Production of Humanized Monoclonal Antibody: Development, Expression and Characterization of Humanized AntiC2 M,Used

Development and Production of Humanized Monoclonal Antibody: Development, Expression and Characterization of Humanized AntiC2 M,Used

In Stock
SKU: DADAX365921311X
Brand: LAP Lambert Academic Publishing
$124.05 $177.21
Save $53.16
Quantity
Add to wishlist
Add to compare

Processing time: 1-3 days

US Orders Ships in: 3-5 days

International Orders Ships in: 8-12 days

Return Policy: 15-days return on defective items

Payment Option
Payment Methods

Help

If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.

Customer service

All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com

Sale & Press

If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com

The treatment of cancer remains a formidable challenge owing to the difficulties in differentiating tumor from nontumor cells in order to ameliorate the disease without causing intolerable toxicity to human patients. The use of monoclonal antibodies (mAbs) represents an attractive approach of overcoming this problem as the mAbs can be designed to selectively target tumor cells and elicit a variety of responses once bound. However, when rodent mAbs are administered in humans, antiantibody responses are frequently observed. Hence, humanized monoclonal antibodies are instead widely used for diagnosis and treatment of cancer due to their reduced immunogenicity and high specificity. In this book, two humanization methods were utilized for the development of humanized mAb (humC2 mAbs) against C2antigen, a marker expressed in colorectal and ovarian cancer, from mAb of mouse origin. Various procedures were also developed to produce humC2 mAbs, with high efficiency in terms continuity of production, lowered cost and increased speed. In addition, highthroughput and automated systems were also utilized to facilitate the upstream and downstream phases of humC2 mAbs.

⚠️ WARNING (California Proposition 65):

This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.

For more information, please visit www.P65Warnings.ca.gov.

Recently Viewed