Title
Diamines in Catalysis and in Biological Systems: Analysis and Applications,Used
Delivery time: 8-12 business days (International)
Currently there is a lot of interest in developing new methods for making chiral 1,2diamines since they are building blocks not only for stereoselective catalysts, but also for a variety of therapeutic agents. Optically pure 1,2diamines (or vicinal diamines) are used as organocatalysts in aldol condensation, Michael addition15 and DielsAlder reactions or as metal ligands for stereoselective epoxidation, hydrogenation and dihydroxylation. In the realm of biology and biochemistry, diamine functionality is found in 1,2diamino acids, lactam antibiotics and various pharmaceuticals. In chemotherapy, platinum 1,2diamino complexes have long been used as antitumor agents. All these utilizations stimulated further research in the field of diamine synthesis. Numerous strategies have been developed to meet this need including coupling of bisimines using low valent transition metals, preparation and subsequent reduction of diketones or addition of nitrogen sources to aziridine and epoxide moieties. This book describes novel methods which are more efficient and less cumbersome in preparation of chiral vicinal diamines.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
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This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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