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This outstanding volume provides comprehensive coverage of each dopamine receptor/transporter system, including uptodate reviews of the molecular biology, gene evolution, pharmacology, topology, signal transduction properties, anatomical distribution, and regulation. Explains the genetic characterization of the dopamine receptor/transporter gene family and its relationship to the etiology and maintenance of neuropsychiatric disorders as well as its role in antipsychotic drug action! Examining the history, current status, and future of the field, Dopamine Receptors and Transporters describes the development and chemistry of specific dopamine receptor ligands elucidates pharmacological and biochemical identification and the distribution of dopaminergic pathways in the brain discusses the functional properties of dopamine receptor stimulation and their importance in neuropsychiatric diseases explores the regulation of gene transcription, receptor mRNA distribution, and genetic linkage illustrates the molecular biology and pharmacology of the dopamine transporter addresses the sodiumdependent transport system and vesicular transporters and more!
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