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Bindng
Duchenne Muscular Dystrophy
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Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is one of the most common single gene disorders found in the developed world.In this third edition of the classic monograph on the topic, Alan Emery is joined by Francesco Muntoni, Professor of Paediatric Neurology, to provide a thorough update on all aspects of the disorder.Identification of the genetic defect responsible for Duchenne Muscular Dystrophy and isolation of the protein dystrophin have led to the development of new theories for the diseases pathogenesis. This new edition incorporates these advances from the field of molecular biology, and describes the resultant opportunities for screening, prenatal diagnosis, genetic counselling and management. Although there is still no cure for the disorder, there have been significant developments in understanding the progression of the disease, and advances in the management of respiratory and cardiac symptoms. Emery and Muntoni also explore and speculate on the possibilities for future treatments employing drugs and gene therapies.This book will appeal not only to scientists and clinicians, but also to a wide range of therapists and other professionals involvd in the care of patients with muscular dystrophy.
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