Title
El mundo desconocido del cido pipeclico: Componente y precursor de metabolitos secundarios con importantes actividades biol,Used
Delivery time: 8-12 business days (International)
En primer lugar, en el presente trabajo de investigacin, se demostr que Penicillium chrysogenum es capaz de utilizar cido pipeclico para complementar los requerimientos nutricionales de mutantes auxtrofos de lisina (lys). La clonacin del gen que codifica la sacaropina reductasa (gen lys7) y la caracterizacin bioqumica y molecular de mutantes auxtrofos de lisina e incapaces de utilizar cido pipeclico para complementar dicha auxotrofa (lys/Pip), permitieron determinar que en este hongo filamentoso el cido pipeclico se convierte en lisina. En segundo lugar, se demostr que P. chrysogenum es capaz de sintetizar cido pipeclico. El gen lys7 fue interrumpido por la tcnica de la doble recombinacin. La cepa interrumpida (SR1) es auxtrofa de lisina y acumula altos niveles de P6C cuando se crece con Llisina como nica fuente de nitrgeno y se aade cido D,Lalfaaminoadpico (AAA) al medio de cultivo, demostrndose que el cido pipeclico se sintetiza a partir del AAA y no a partir del catabolismo de lisina. La cepa SR1 podra utilizarse para producir metabolitos secundarios que contengan cido pipeclico con interesantes actividades farmacolgicas.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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