If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
Help
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
En primer lugar, en el presente trabajo de investigacin, se demostr que Penicillium chrysogenum es capaz de utilizar cido pipeclico para complementar los requerimientos nutricionales de mutantes auxtrofos de lisina (lys). La clonacin del gen que codifica la sacaropina reductasa (gen lys7) y la caracterizacin bioqumica y molecular de mutantes auxtrofos de lisina e incapaces de utilizar cido pipeclico para complementar dicha auxotrofa (lys/Pip), permitieron determinar que en este hongo filamentoso el cido pipeclico se convierte en lisina. En segundo lugar, se demostr que P. chrysogenum es capaz de sintetizar cido pipeclico. El gen lys7 fue interrumpido por la tcnica de la doble recombinacin. La cepa interrumpida (SR1) es auxtrofa de lisina y acumula altos niveles de P6C cuando se crece con Llisina como nica fuente de nitrgeno y se aade cido D,Lalfaaminoadpico (AAA) al medio de cultivo, demostrndose que el cido pipeclico se sintetiza a partir del AAA y no a partir del catabolismo de lisina. La cepa SR1 podra utilizarse para producir metabolitos secundarios que contengan cido pipeclico con interesantes actividades farmacolgicas.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer,
birth defects, or other reproductive harm.
For MAP (Minimum Advertised Price) violations and Intellectual Property (IP) or Trademark concerns, please contact:
support@ergodebooks.com
⚠️ California Proposition 65 Warning: Some products sold on this website may expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
