Title
Electrospray Ionisation Mass Spectrometry: Ion Suppression in Electrospray Ionisation Mass Spectrometry,Used
Delivery time: 8-12 business days (International)
Electrospray ionization mass spectrometry (ESIMS) coupled to reversephase high performance liquid chromatography (RPHPLC) has emerged as one of the most powerful techniques for the analysis of biochemical and pharmaceutical compounds. Trifluoroacetic acid (TFA) is a commonly used additive in HPLC and LCMS analysis of basic compounds. However, TFA is known to suppress the ESI signals of analytes due to its ability to form strong gasphase ion pairs with positivelycharged analyte ions. This ionpairing process masks the sample positivelycharged analyte ions/cations from the ESIMS electric field by rendering them neutral. To overcome the signal suppression effect of TFA on basic compounds, we studied a simple and very effective means of minimizing the negative effect of TFA in analysis of aniline, caffeine, arginine and glutamine by addition of acetic acid or propionic acid to analyte solution containing 0.05% TFA. A factor of up to two fold signal enhancement (for arginine and glutamine) and full original signal recovery (for caffeine) were achieved.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.