Title
Electrospray Ionisation Mass Spectrometry: Ion Suppression in Electrospray Ionisation Mass Spectrometry,Used
Sold by Ergodebooks, an authorized reseller.
Returns accepted within 30 days | support@ergodebooks.com
Shipping Information
- Free Standard Shipping — United States only
- Processing Time: 1–3 business days
- Estimated Delivery: 3–5 business days after dispatch
- Double-boxed, fully insured & discreetly packaged
- Tracking number sent via email once dispatched
- Orders over $250 require signature upon delivery. Taxes calculated at checkout.
Returns & Refund
Returns accepted within 30 days of delivery.
Damaged or Defective Item
Free return shipping + replacement or full refund
Wrong Item Received
Free return shipping + replacement or full refund
Change of Mind
Return shipping at customer's expense · 25% restocking fee applies
Payment Option
Electrospray ionization mass spectrometry (ESIMS) coupled to reversephase high performance liquid chromatography (RPHPLC) has emerged as one of the most powerful techniques for the analysis of biochemical and pharmaceutical compounds. Trifluoroacetic acid (TFA) is a commonly used additive in HPLC and LCMS analysis of basic compounds. However, TFA is known to suppress the ESI signals of analytes due to its ability to form strong gasphase ion pairs with positivelycharged analyte ions. This ionpairing process masks the sample positivelycharged analyte ions/cations from the ESIMS electric field by rendering them neutral. To overcome the signal suppression effect of TFA on basic compounds, we studied a simple and very effective means of minimizing the negative effect of TFA in analysis of aniline, caffeine, arginine and glutamine by addition of acetic acid or propionic acid to analyte solution containing 0.05% TFA. A factor of up to two fold signal enhancement (for arginine and glutamine) and full original signal recovery (for caffeine) were achieved.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.