Title
Endothelin1 in Endotoxin and SepsisInduced Lung Injury,Used
Delivery time: 8-12 business days (International)
Acute lung injury (ALI) is a common complication of different conditions like sepsis, shock and trauma, which may emerge into fullblown acute respiratory distress syndrome (ARDS). During the last 15 years, participation of the endothelin1 (ET1) system in the pathogenesis of ALI/ARDS has been intensively studied. In sepsisinduced acute lung injury (ALI), endothelin1 (ET1) is suspected of increasing lung capillary pressure and probably permeability. In present study, we studied pulmonary hemodynamic, volumetric and permeability effects of the nonselective ET1 receptor antagonist, tezosentan, in animals with endotoxin or sepsisinduced ALI. We also studied the activation of protein kinase C alpha and expression of mRNA for preproET1 and its receptors in animals lung tissue cells. Additionally, we investigated the relationship between the plasma concentration of ET1 and extravascular lung water index (EVLWI) in septicemic patients.
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This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.