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The present investigation deals with continuous ethanol production from date syrup by using a flocculent yeast. The main portion of the system consisted of a jacketed cylindrical Pyrex glass bioreactor where the date syrup was pumped from its base and the product was received from the top. BoxWilson composite rotatable design was constructed to obtain the proper conditions of ethanol fermentation [temperature, date syrup concentration and feeding flow rate]. It is possible to obtain from this technique a polynomial equation which describes how these variables affect ethanol production. The optimum conditions are: Temperature: 29.5 C, Date syrup concentration: 64.47 mg/cm3, Feeding flow rate: 200 cm3/hr. The study shows that flocculent yeast is more efficient in continuous ethanol production process when it is compared with nonflocculent yeast. Flocculent yeast cells are able to aggregate and make flocs so that, the cells will remain in the column. Date syrup was used in this research as a sugar substrate because it was the available sugar source in Iraq and usually used in ethanol production. Maximum conversion of date syrup to ethanol is 92.99%.
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