Title
Etude fonctionnelle de Fkbp25 et Fkbp36 dans le dveloppement neuronal: Des cellules souches aux neurones (Omn.Pres.Franc.) (Fr,Used
Delivery time: 8-12 business days (International)
Le dveloppement du cerveau humain sorganise autour de trois tapes majeures, la prolifration, la migration et la diffrentiation des cellules neuronales. Ces 3 tapes font intervenir d'importants remaniements du cytosquelette cellulaire, compos d'actine et de microtubules. Les protines associes aux microtubules ont donc un rle majeur au cours du dveloppement et pour preuve, des mutations de ces protines entranent des maladies neurodveloppementales telles que la lissencphalie, la schizophrnie ou le syndrome de lX fragile. Dans ce travail, nous avons clon deux gnes codant des immunophilines, Fkbp25 et Fkbp36 qui se localisent au niveau du centrosome et du fuseau mitotique et dont la surexpression in vivo et in vitro module la division cellulaire et la croissance dendritique des cellules souches et des neurones corticaux. Ces protines font partie de complexes diffrents associant la protine de l'X fragile FMRP pour Fkbp25 et la LimK2b pour Fkbp36, suggrant qu'elles agissent dans des voies de signalisation distinctes. Cet ouvrage est destin tous les acteurs de la recherche franaise.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.