Title
EXPRESSION OF Fc?RIII, CR3, TNFalpha AND NO PRODUCTION BY MONOCYTES: EXPRESSION OF Fc?RIII, CR3, INTRACELLULAR TNFalpha AND NI,Used
Delivery time: 8-12 business days (International)
Severe Plasmodium falciparum Malaria is a major cause of childhood mortality in SubSaharan Africa. A clear understanding of the factors that play a role in It'spathogenesis is essential for the development of effective prophylactic and therapeutic measures. Fc gamma receptor III (Fc? RIII) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgGcoated uninfected red cells and by allowing the production of TNF? and nitric oxide (NO) upon crosslinking by immune complexes (ICs). However, phagocytosis via complement receptor 3 (CR3) suppresses proinflammatory monocyte functions such as NO production. Therefore, the expression levels of these receptors on monocytes/macrophages may influence degree of stimulation and determine individuals' susceptibility to severe malaria. This study examined the expression of Fc?RIII and CR3 on monocytes of children with severe malarial anaemia, cerebral malaria, and their age and gendermatched uncomplicated malaria controls by flow cytometry.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.