Title
Formulation and Evaluation of Buspirone Hydrochloride Buccal Films: Buspirone Hydrochloride Buccal Films,Used
Delivery time: 8-12 business days (International)
Buspirone Hydrochloride is used in the treatment of anxiety. It has a short half life and low oral bioavailability of 5%. Therefore, the purpose of this research was to develop unidirectional Bucco adhesive films of Buspirone Hydrochloride by solvent casting technique using full factorial designs. HPMC K15M and Eudragit RL100 were used as polymers in different proportion. Polyethylene glycol 400 was used as plasticizer and Sodium lauryl sulphate was used as permeation enhancer in different concentration. The physicochemical compatibility of the drug and the polymers was studied by FTIR spectroscopy. The results suggested no physicochemical incompatibility between the drug and the polymers. In full factorial designs, total amount of polymer (X1) and percentage of HPMC K15M (X2) was kept as a independent variables. After wards, statistically optimization process was carried out and two optimized formulation (OF1 and OF2) was developed. The results of optimization formulation showed greater degree of % similarity with predicted values. Stability studies of two optimized formulations were carried out at room temperature as per ICH Q1C guidelines.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.