Geometrical Probability and Biological Structures: Buffons 200th Anniversary: Proceedings of the Buffon Bicentenary Symposium on,Used

Geometrical Probability and Biological Structures: Buffons 200th Anniversary: Proceedings of the Buffon Bicentenary Symposium on,Used

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L'etude morphologique des tissus pathologiques en microscopie d' elements: optique comporte schematiquement deux types 1) les cellules, 2) les Fibres conjonctives intercellulaires. Ces Fibres, qui constituent Ie 'squelette mou', servent de support aux elements cellwlaires, contribuent a maintenir l'architecture des tissu, et interviennent dans la circulation des liquides intercellu laires. La quantite, la structure et la repartition de ces Fibres sont etroitement liees a l'activite physiologique des populations cellulaires et a leur pathologie.L'etude de leurs modiFications est tres utile dans Ie diagnostic d'une lesion, mais la complexite et la variete des images de ces reseaux Fibrillaires rend leur description et leur classiFication tres diFFiciles. L'application des methodes morphometriques peut etre un moyen utile pour obtenir des parametres objectiFs susceptibles de preciser ces structures. C'est uniquement l'etude des Fibres conjonctives que nous envisa gerons pour Ie moment. L'emploi, en pratique courante, des methodes morphometriques comme aide au diagnostic anatomopathologique, ne peut se concevoir que si les techniques utilisees sont relativement simples et surtout rapides. Dans ce but, nous avons entrepris, depuis I973, avec les moyens du Laboratoire, la realisation d'un appareil automatique specialement con u pour essayer de repondre aux exigences particulieres de ce type d' e'tudes.

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