Granulocyte Responses to Cytokines: Basic and Clinical Research (Immunology),Used

Granulocyte Responses to Cytokines: Basic and Clinical Research (Immunology),Used

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Brand: CRC Press
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This volume explores the basic physiological functions of granulocytes, their modification by cytokines, and the clinical experience with cytokines discussing the specific responses of neutrophils, eosinophils, basophils, and mast cells to individual cytokines.;Written by more than 60 experts from all over the world, Granulocyte Responses to Cytokines ...: examines the responses of granulocytes and mast cells to hormones, chemotactic peptides, and phorbol esters; details cytokine effects on morphology, micration, adhesion, phagocytosis, degranulation, and cytotoxicity against tumour cells and pathogens; covers cyclic nucleotide, protein kinases, G proteins, lipoxygenase, and leukotrienes in the regulation of granulocyte functions; indicates caution in the use of cytokine therapy for certain leukaemias due to cytokine effects on the growth of malignant cells; and presents clinical studies with granulocytemacrophage and granulocyte colonystimulating factors with promising results in treating genetic, virus, and druginduced granulocytopenias and immunodeficiencies.;Containing nearly 3900 literature citations, Granulocyte Responses to Cytokines is a guide for immunologists; hematologists; oncologists; pharmacologists; biologists, microbiologists, and biochemists; pathologists; internists; and graduatelevel students in these disciplines.

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