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This volume provides, for the first time, an extensive compilation of those stateoftheart methods that have revolutionized the use of mice as an experimental system. This volume is a unique source for detailed descriptions to be used in research by both experienced and novice researchers Germ cells and embryos; Fertilization; Gene expression: messenger RNA, reporter genes, proteins, methylation; Gene identification; Nuclear transplantation; Transgenic animals: pronuclear injection, embryonic stem cells, and gene targeting; Lineage analysis.Key Features* Contains the most uptodate methodology as applied to mouse development * Focuses on molecular approaches to experimental mouse development * The first comprehensive source for molecular biological methods in mouse development * Many of the methods have never appeared before
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