Title
In Vitro stressor related changes in ovarian steroidogenesis: In rainbow trout (Oncorhyncus mykiss),Used
Delivery time: 8-12 business days (International)
The study examined the affect of cortisol on basal and cAMPstimulated in vitro steroidogenesis of rainbow trout (Oncorhynchus mykiss) ovarian follicles at different maturational stages. Basal and cAMPstimulated 17estradiol (E2) and testosterone (T) production was highest during the midvitellogenic (MV) stage, compared with early and latevitellogenic stages. Cortisol suppressed the basal steroid production in the MV stage, and suppressed cAMPstimulated steroid production in all three maturational stages. To determine whether cortisol exerts its effect on pregnenolone (P5) production, real time RTPCR was used to measure the expression of genes coding for steroidogenic acute regulatory (StAR) protein, and cytochrome P450scc. There was no significant affect of cortisol on the expression of either gene. To look for possible actions of cortisol on steroidogenic enzyme function, the effect of the glucocorticoid on the biotransformation of radiolabelled P5, and T was examined; cortisol appeared to suppress the aromatization of androgens to estrogens by a mechanism that is not fully understood.
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For more information, please visit www.P65Warnings.ca.gov.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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