Title
KineticStudy of Diclofenac Sodium from MethocelK15MCR and Cetylalcohol: Using Model dependent and Independent Methods and Bioequ,Used
Delivery time: 8-12 business days (International)
Current study aimed at the development of a matrix type sustain release Diclofenac tablet, using hydrophilic HPMC and hydrophobic polymer Cetyl alcohol. It was found that hydrophilic Methocel K15 MCR matrices based tablets showed zero order and hydrophobic cetyl alcohol matrices based tablets were followed firstorder kinetics except formulation six (F6 showed zero order profile). The result of dissolution study indicated that formulations containing cetyl alcohol showed better dissolution properties as compared to formulations containing Methocel K15 MCR in terms of similarity and difference factor. By comparing the dissolution profiles with Voltaren SR tablet in terms of difference factors and similarity factors, it was revealed that the formulation F4, F5 and F6 exhibited similar drug release profile as that of Voltaren SR tablet which indicated that these formulations could be bioequivalent with Voltaren SR tablet in vitro. The present study demonstrated that Diclofenac could be successfully prepared using an appropriate amount of Methocel K15 MCR and cetyl alcohol in the form of matrix tablets with similar dissolution profile of patent product Voltaren SR.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.