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Over the past two decades the benefits of labelfree biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories.LabelFree Technologies For Drug Discovery summarises the latest and emerging developments in labelfree detection systems, their underlying technology principles and enduser case studies that reveal the power and limitations of labelfree in all areas of drug discovery.Labelfree technologies discussed include SPR, NMR, highthroughput mass spectrometry, resonant waveguide platebased screening, transmittedlight imaging, isothermal titration calorimetry, optical and impedance cellbased assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, highcontent technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cellbased receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.LabelFree Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly highthroughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.
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⚠️ California Proposition 65 Warning: Some products sold on this website may expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
