Lipoprotenas de baja densidad y remanentes lipoproteicos en humanos: Diferentes mecanismos de oxidacin y aterognesis (Span,Used

Lipoprotenas de baja densidad y remanentes lipoproteicos en humanos: Diferentes mecanismos de oxidacin y aterognesis (Span,Used

SKU: DADAX3848456273 In Stock
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Delivery time: 3-5 business days (USA)
Delivery time: 8-12 business days (International)
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A diferencia de las LDL nativas, no modificadas, que poseen una una sola copia de Apolipoprotena B, las LPRs son el producto intermedio del catabolismo de la lipoprotenas de muy baja densidad (VLDL) de origen heptico conteniendo Apo B 100 y de los quilomicrones remanentes(QR), con apo B 48, respectivamente. Ambas aumentan en condiciones postprandiales, y tambin contienen Apo C. Las LDL deben oxidarse en el subendotelio vascular, donde son captadas por monocitos/macrfagos, que se transforman en clulas espumosas cuando LDL oxidadas entran va el receptor scavenger, que permite su acumulacin. En cambio, LPRs tienen sus sitios de oxidacin en los elementos formes sanguneos y en las clulas endoteliales. Ambas lipoprotenas son aterognicas pero LPRs activan el receptor LPOX1 de clulas endoteliales, abriendo brechas en el endotelio injuriado, permitiendo el pasaje de citoquinas y otros elementos aterognicos. Tambin son captadas por los macrfagos, sin previa oxidacin y promueven procesos inflamatorios con aumento de la Protena C reactiva (PCR de alta sensibilidad).

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Shipping & Returns

Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

Warranty

We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.

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