Lokale IgGProduktion im Liquor bei multipler Sklerose (Schriftenreihe Neurologie Neurology Series, 30) (German Edition),Used

Lokale IgGProduktion im Liquor bei multipler Sklerose (Schriftenreihe Neurologie Neurology Series, 30) (German Edition),Used

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Methodische Fortschritte in der Liquordiagnostik zwingen auch zu neuen Einsichten uber die physikochemischen Voraussetzungen dia gnostischer Verfahren und zu differenzierteren Interpretationen der Befunde in Relation zur klinischen Situation. Die Analyse der Liquor proteine nimmt dabei eine zentrale Stellung ein. Die bis vor etwa 40 Jahren nur grobe Unterteilung in Albumin und Globulin erfuhr mit der Entwicklung elektrophoretischer Methoden eine entscheidende Verfei nerung, die zu einer immer praziseren Identifikation zahlreicher Pro teinkomponenten fuhrte. Dabei stand die Untersuchung des Immun globulin G im Mittelpunkt. Diese Monographie befasst sich mit den grundlegenden Aspekten des Immunglobulin G bei der multiplen Sklerose. Hinsichtlich der Metho dik sind dabei wesentlich: erstens die exakte, simultane, quantitative Bestimmung des Proteins und seiner Komponenten im Liquor und im Blutserum und die Errechnung der intrathekalen ImmunglobulinG Produktion unter Berucksichtigung der Bluthirnschrankenfunktion und zweitens die differenzierte Analyse der oligoklonalen Banden im IgG Bereich mittels der isoelektrischen Fokussierung. Die Information, die sich im Hinblick auf Diagnose und Verlauf der Erkrankung ergibt, wird dargestellt und kritisch bewertet. Das Ergebnis der Studie von Herrn Schipper ist eine informative Darlegung derzeitiger Erkenntnisse uber das Immunglobulin G, die durch die Liquoruntersuchung am Krankenbett ermittelt werden kon nen und fur alle weiteren differenzierteren biochemischen und immu nologischen Befunde unverzichtbares Basiswissen darstellen. H. J. Bauer v Diese Arbeit stellt einen in sich abgeschlossenen Auszug aus der mit dem HeinrichPettePreis der Deutschen Gesellschaft fur Neurologie ausgezeichneten Habilitationsschrift des Verfassers 'Lokale IgGProduktion im Zentralnervensystem' dar. Sie wurde dem aktuellen Stand der literatur entsprechend erganzt.'

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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Warranty

We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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