Methods for the Discovery and Characterization of G ProteinCoupled Receptors (Neuromethods, 60),Used

From the Back CoverThe goal of the characterization and discovery of G proteincoupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies. In Methods for the Discovery and Characterization of G ProteinCoupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the readers particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors. Chapters also feature an important section called Future Directions which gives the reader an insight into advances soon to be realized in each area. Written for the popular Neuromethods series, this book contains the kind of detailed description and implementation advice that is crucial for getting optimal results.Authoritative and cuttingedge, Methods for the Discovery and Characterization of G ProteinCoupled Receptors serves as an ideal guide for scientists determined to further our knowledge of crucially important set of receptors.Product DescriptionThe goal of the characterization and discovery of G proteincoupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies. In Methods for the Discovery and Characterization of G ProteinCoupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the readers particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors. Chapters also feature an important section called Future Directions which gives the reader an insight into advances soon to be realized in each area. Written for the popular Neuromethods series, this book contains the kind of detailed description and implementation advice that is crucial for getting optimal results.Authoritative and cuttingedge, Methods for the Discovery and Characterization of G ProteinCoupled Receptors serves as an ideal guide for scientists determined to further our knowledge of crucially important set of receptors.ReviewFrom the reviews:Methods for the Discovery and Characterization of G ProteinCoupled Receptors is an excellent reference text for anyone concerned with the dynamic life of GPCRs in living tissues. The book is suitably organized to cater to a wide audience, and the material is presented in a logical framework to permit understanding of major concepts by a novice. This would be a particularly valuable book for any structural biologist looking to build complexity into their experimental system to account for in vivo phenomena. (Michelle OMalley, ChemBioChem, Vol. 13 (6), April, 2012)