Title
Microsponge Based Colonic Drug Delivery Systems: Development and Characterization of Microsponge Based Colonic Drug Delivery Sys,Used
Delivery time: 8-12 business days (International)
This study encompasses preparation microsponges based colon specific tablet formulations. Initially, microsponges of dicyclomine and paracetamol were prepared by quasiemulsion solvent diffusion method. The reason for preparing microsponge due to the fact that, drug carrier systems less than 200 ?m may efficiently be taken up by the macrophages present in colon tissue, thus exhibit effective localized drug action at the desired site. A subsequent increase of residence time that may be postulated for microsponges as compared to existing drug delivery systems may allow dose reduction and enhance therapeutic effect. Another reason for preparing microsponges was their sponge like texture that can easily be compressed by direct compression for producing mechanically strong tablets. Then core tablets of microsponges were prepared by direct compression method and were compression coated with pectin:HPMC mixture. The reason for selecting pectin was its biodegradation in the colon by colonic flora. HPMC is reported to increase the mechanical strength of the tablet coat and helped in maintaining its integrity during its sojourn in the gastrointestinal tract.
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Shipping & Returns
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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