Title
Modeling diffusion controlled reactions in living cells: A solution to the subdiffusionefficiency paradox of EcoRV enzyme in E.,Used
Sold by Ergodebooks, an authorized reseller.
Returns accepted within 30 days | support@ergodebooks.com
Shipping Information
- Free Standard Shipping — United States only
- Processing Time: 1–3 business days
- Estimated Delivery: 3–5 business days after dispatch
- Double-boxed, fully insured & discreetly packaged
- Tracking number sent via email once dispatched
- Orders over $250 require signature upon delivery. Taxes calculated at checkout.
Returns & Refund
Returns accepted within 30 days of delivery.
Damaged or Defective Item
Free return shipping + replacement or full refund
Wrong Item Received
Free return shipping + replacement or full refund
Change of Mind
Return shipping at customer's expense · 25% restocking fee applies
Payment Option
Macromolecular crowding in living biological cells effects subdiffusion of larger biomolecules such as proteins and enzymes. Mimicking this subdiffusion in terms of random walks on a critical percolation cluster, fractional Brownian motion and continuous time random walk, we here present a case study of EcoRV restriction enzymes involved in vital cellular defence. EcoRV has been found in two configurational states. We show that due to its so far elusive propensity to an inactive state the enzyme avoids nonspecific binding and remains welldistributed in the bulk cytoplasm of the cell. Despite the reduced volume exploration of subdiffusion processes, the low activity of the enzyme surprisingly guarantees a high efficiency of the enzyme. Our results corroborate a more local picture of cellular regulation and demonstrated a solution to subdiffusionefficiency paradox; Specific molecular design renders the efficiency of EcoRV enzymes almost independent on the exact diffusion conditions. This case study also provides us a chance to compare different subdiffusive processes in living cells and guides us to a broader understating of diffusion controlled reactions in living cells.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.