Title
Molecular Effect of Resveratrol on Neurodegeneration Induced In Rats,Used
Delivery time: 8-12 business days (International)
The crosstalk between neurons and nonneuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Aluminum is a well documented neurotoxin, resulting from the fact that it replaces the usual metal ions in proteins and enzymes, causing a change in the replication rate or decreasing the metabolic rate which may triggers neuronal damage. The plant polyphenol resveratrol has been touted to have multiple health benefits including neuroprotection. A commonly cited mechanism of resveratrol action is via the activation of the longevity factor Sir2/Sirt1, whose deacetylase activity on several transcription factors has stress resistance and prosurvival effects. In this study we propose APE1/Ref1 (APE1), a multifunctional protein possessing both DNA repair and transcriptional regulatory activities, as newb reserveratrolmediated neuroprotection target. We believe that understanding the molecular balance between total oxidant versus antioxidant capacities as well as proapoptotic versus prosurvival proteins during neuroinflammation is essential for therapeutics development.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
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