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Legionnaires disease, a potentially fatal type of pneumonia primarily affecting elderly and immunocompromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogenhost interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a stateoftheart overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
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