MPO als Prognosemarker bei Patienten mit PAH: Eine klinische Studie (German Edition),Used

MPO als Prognosemarker bei Patienten mit PAH: Eine klinische Studie (German Edition),Used

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Die Pulmonalarterielle Hypertonie (PAH) ist eine schwere Erkrankung mit hoher Mortalitt, bei der es durch ein Zusammenspiel von Proliferation, Inflammation und endothelialer Dysfunktion zur Muskularisierung der Lungenarterien und einer Vernderung des Geftonus kommt. Die verminderte Bioverfgbarkeit von Stickstoffmonoxid (NO) wird dabei als ein wichtiges Krankheitsmerkmal angesehen. Der Auslser sowie die genauen Mechanismen der Erkrankung sind jedoch unbekannt. Myeloperoxidase (MPO) ist ein Hmprotein, das von Leukozyten freigesetzt wird und die Fhigkeit besitzt, im subendothelialen Raum zu akkumulieren. Dort oxidiert MPO endothelial generiertes NO. Whrend Studien die Bedeutung von Leukozytenaktivierung und MPOAktivitt fr Erkrankungen wie Vorhofflimmern und Linksherzinsuffizienz gezeigt haben, fehlen solche Daten fr die PAH und die chronische Rechtsherzinsuffizienz. In dieser klinischen Studie werden im ersten Teil die MPOPlasmaspiegel einer PAHPatientengruppe mit denen eines Kontrollkollektivs verglichen. Im zweiten Teil wird die Aussagekraft des MPOSpiegels auf die Krankheitsschwere und die Prognose der PAHPatienten in einer Verlaufsbeobachtung untersucht.

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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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