Natural Antioxidants: An Approach Towards Tuberculosis Management: Green Tea Polyphenol (EGCG) as Potential Adjunct in Combating,Used

Natural Antioxidants: An Approach Towards Tuberculosis Management: Green Tea Polyphenol (EGCG) as Potential Adjunct in Combating,Used

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Tuberculosis (TB) has been reported to have fifth highest fatality rate in the world, a disease claiming between 2 and 3 million lives a year. One of the important reasons why this killer parasite is spiraling out of control at an alarming rate is attributed to the prevalence of multidrugresistant (MDR) strains and emergence of AIDSrelated TB. Focus has now been shifted towards development of compounds from natural sources that have antimycobacterial activity. The incorporation of such compounds, like polyphenols namely Epigallocatechin3gallate (EGCG) from green tea, as the natural component of tuberculosis treatments has been studied here. Reactive oxygen species and tumor necrosis factor (TNF?) are the hallmarks of tuberculosis. The augmented expression of TNF? at both the gene and protein levels in MTBinfected monocytes is suppressed by EGCG in dosedependent manner. Also,EGCG ameliorated the IFN? levels, the glutathione peroxidase activity, which correlated inversely with the downregulation of ROS and TNF ? in MTBinfected monocytes. Hence, EGCG may prove to be a valuable natural antioxidant in tuberculosis management.

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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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Warranty

We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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