Title
Neutral nonequilibrium population genetics,Used
Delivery time: 8-12 business days (International)
The detection of genomic regions that have been targeted by natural selection is a fundamental objective in population genetics. For this purpose and based on the concept of coalescent theory, several statistics were derived to test the neutral model of molecular evolution under the assumption of constant population size. However, within the last decade it became evident that this assumption is not warranted in many biological model organisms. For this reason, established theoretical results on neutral nonequilibrium models are extended within this work to obtain the secondorder moments of various tree size and DNA polymorphism measures. Then, the obtained results are embedded in generalized versions of statistical tests to provide the possibility for testing the neutral model under variable population size, using two datasets of Drosophila melanogaster. Finally, the feasibility of the approach is further illustrated with the aid of several examples of various demographic scenarios. In conclusion, limitations and open research questions are discussed.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
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