Neyro i psikhotropnye effekty benzimidazola i ego proizvodnykh: Kniga prednaznachena dlya issledovateley v oblasti neyrofiziolo,Used

Neyro i psikhotropnye effekty benzimidazola i ego proizvodnykh: Kniga prednaznachena dlya issledovateley v oblasti neyrofiziolo,Used

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SKU: DADAX3846581178
Brand: LAP Lambert Academic Publishing
Condition: New
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Vpervye s ispol'zovaniem metodov vnutrikletochnogo otvedeniya biopotentsialov i analiza krivykh pervoy proizvodnoy potentsialov deystviya bylo issledovano vliyanie benzimidazola i nekotorykh ego proizvodnykh na elektricheskuyu aktivnost' neyronov vinogradnoy ulitki. Pokazano, chto deystvie issledovannykh soedineniy zavisit ot ikh khimicheskoy struktury i tipa neyronov, membrany kotorykh obladayut vyrazhennoy spetsifichnost'yu, obuslovlennoy kharakternoy dlya kazhdogo tipa neyronov kombinatsiey ionnykh kanalov. Opredeleny porogovye , optimal'nye i toksicheskie kontsentratsii testiruemykh veshchestv. Ustanovleno, chto pri odnokratnom vnutribryushinnom vvedenii 50 mg/kg rastvora testiruemykh veshchestv odni proizvodnye aktiviruyut lokomotsiyu i psikhoemotsional'noe sostoyanie krys i, sledovatel'no, mogut obladat' psikhistimuliruyushchimi svoystvami, a drugie ugnetayut dannye pokazateli, to est' obladayut antistressornm deystviem. V vysokikh dozakh 100 i 150 mg/kg vse issledovannye veshchestva generalizovano ugnetayut povedencheskie reaktsii zhivotnykh, okazyvaya moshchnoe sedetivnoe deystvie.

⚠️ WARNING (California Proposition 65):

This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.

For more information, please visit www.P65Warnings.ca.gov.

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