Title
Overcoming The Glial Scar After Spinal Cord Injury: A Preclinical Outlook,Used
Delivery time: 8-12 business days (International)
Damaged neurons in the CNS generally fail to regenerate after spinal cord injury (SCI), which may be due in part to the formation of the glial scar, a biochemical and physical barrier against axon growth. Here we report on evidence for 3 major conclusions. 1) Antibodymediated blockade of the growthinhibitory NG2 molecule found in glial scars is a viable strategy to promote sensory axon regeneration. 2) A combinatorial treatment approach that neutralizes extrinsic inhibition and stimulates intrinsic neuronal growth capacity is an important strategic consideration because this method can promote longdistance, anatomically correct axon regeneration. Accurate growth trajectory is a prerequisite for functional recovery. 3) After SCI and growth promoting treatments, regenerated axons remain chronically demyelinated and exhibit pathophysiological function, similar to that observed in cases of multiple sclerosis. This suggests the need for further treatments designed to restore normal axon conduction after SCI. Overall, a cure for paralysis after SCI requires that we crudely reproduce what the developing nervous system does naturally with precision.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.