Oxidative Neural Injury (Contemporary Clinical Neuroscience),Used

Oxidative Neural Injury (Contemporary Clinical Neuroscience),Used

SKU: DADAX1603273417
Categories : Science & Math
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Categories : Science & Math

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Twentyfive years ago, Earl R. Stadtman, PhD discovered that specific enzymes regulating metabolism can be inactivated by oxidation [1]. He later showed that agerelated oxidative modification contributes, at least in part, to agerelated loss of function of the enzymes [2, 3]. Dr. Stadtman broke the ground for a new field of study to discover how oxidative stress contributes in significant ways to agerelated cellular dysfunction and protein accumulation and that oxidation in the aging brain influences Alzheimers disease, ischemiareperfusion injury, amyotrophic lateral sclerosis, and lifespan [46]. Today, his research and mentorship have positively influenced the work of hundreds of scientists in this field. We dedicate this book to Dr. Earl R. Stadtman (19122008), in celebration of his passion for science and his superior collaborative and mentorship skills. This book is comprised of three sections. The first describes the valuable roles reactive oxygen species (ROS) and reactive nitrogen species (RNS) play in cellular biology. The second section provides an overview of redox imbalance injury with effects on mitochondria, signaling, endoplasmic reticular function, and on aging in general. The third section takes these mechanisms to neurodegenerative disorders and provides a stateoftheart look at the roles redox imbalances play in agerelated susceptibility to disease and in the disease processes. In the first section we attempt to answer a question posed by Dr. Stadtman, Why have cells selected reactive oxygen species to regulate cell signaling events [7].

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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

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To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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We provide a 2-year limited warranty, from the date of purchase for all our products.

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