Title
Oxidative Thiol Modifications in Pro and Eukaryotic Organisms: The Influence of Oxidative and Nitrosative Stress on Survival an,Used
Delivery time: 8-12 business days (International)
Oxidative and nitrosative stress has been linked to cell survival, eukaryotic aging and many disease conditions. In this process, highly reactive thiol groups of cysteines undergo reversible oxidative thiol modifications in response to reactive oxygen and nitrogen species. This makes cysteinecontaining proteins the ideal tools to analyze the role of oxidative stress on survival and aging of pro and eukaryotic cells. Here, recent developments in in vivo thiol trapping technology combined with mass spectrometry are used to identify redoxregulated cysteinecontaining proteins in Escherichia coli and Saccharomyces cerevisiae in response to reactive oxygen and nitrogen species. The physiological importance of the identified proteins is then discussed in detail for both organisms. Finally, the redox status of oxidationsensitive proteins in chronological aging yeast is used as in vivo readout to evaluate the role of oxidative stress during the eukaryotic aging process. These studies presented here not only deepened our understanding of redox regulation but also showed the importance of oxidative thiol modifications as key posttranslational modification in pro and eukaryotic cells.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.